Oligodendroglioma
These tumors arise from the supportive tissue of the brain. They can be low grade (II) or high grade (III). The most common location of these tumors is in the cerebral hemispheres, with about half being found in the frontal lobe.
Symptoms
A common first symptom of a low grade tumor is a seizure. If the tumor is frontal, some other common symptoms may include weakness on one side (hemiparesis), problems with memory, poor judgment and personality changes. If the tumor is at the base of the frontal lobe, loss of the sense of smell or impaired vision may occur.
Treatment
Standard treatment of accessible tumors is surgical removal of as much tumor as possible. Biopsy alone may be performed for inaccessible tumors – those that cannot be surgically removed. This biopsy is used to confirm the diagnosis and the grade of the tumor. Close observation with an MRI scan may be indicated. Radiation therapy is indicated if some of the tumor remains after surgery. For higher grade oligodendrogliomas, a combination of radiation therapy and chemotherapy may be indicated.